Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL946900 | 0.87 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL9119690 | 0.82 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9125809 | 0.82 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9121218 | 0.79 | AGTR1 (0.71) | AGTR1 | |
| SCHEMBL9121230 | 0.79 | AGTR1 (0.71) | AGTR1 | |
| SCHEMBL9120388 | 0.78 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9118798 | 0.78 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL8507705 | 0.77 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL20503310 | 0.77 | MAPK1 (0.54) | — | |
| SCHEMBL9128122 | 0.77 | AGTR1 (0.54) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447949-A | Vision defects or cardiovascular disorders | SMITHKLINE BEECHAM CORPORATION (US) | 1995-09-05 | — | — | US | disclosed |
| WO-1992020651-A2 | N-(HETEROARYL)-IMIDAZOLYL-ALKENOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-11-26 | — | — | WO | disclosed |