Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.48 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3324054 | 0.87 | AGTR1 (0.59) | AGTR1AGTR2GP6TLR7 | |
| SCHEMBL9122452 | 0.82 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL4544029 | 0.78 | AGTR1 (0.54) | AGTR1AGTR2GP6 | |
| SCHEMBL9141187 | 0.78 | AGTR1 (0.58) | AGTR1AGTR2GP6 | |
| SCHEMBL15331639 | 0.76 | TLR7 (0.54) | AGTR1AGTR2TLR7 | |
| SCHEMBL9010378 | 0.76 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL14020694 | 0.76 | TLR7 (0.54) | AGTR1AGTR2TLR7 | |
| SCHEMBL1258839 | 0.76 | TLR7 (0.53) | AGTR1AGTR2TLR7 | |
| SCHEMBL359 | 0.74 | GP6 (0.63) | AGTR1AGTR2GP6 | |
| SCHEMBL20503310 | 0.74 | MAPK1 (0.54) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447949-A | Vision defects or cardiovascular disorders | SMITHKLINE BEECHAM CORPORATION (US) | 1995-09-05 | — | — | US | disclosed |
| WO-1992020651-A2 | N-(HETEROARYL)-IMIDAZOLYL-ALKENOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-11-26 | — | — | WO | disclosed |