Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973210 | 0.87 | ALDH1A1 (0.41) | KMT2ATSHRADRB2ADRB1ALDH1A1 | |
| SCHEMBL9121666 | 0.80 | ADRB2 (0.56) | KMT2AADRB2ADRB1 | |
| SCHEMBL1735292 | 0.78 | SCN4A (0.47) | KMT2ATSHRCYP3A4SCN4A | |
| SCHEMBL8778311 | 0.78 | LMNA (0.55) | KMT2ATSHRTP53ALOX15ADRB2 | |
| SCHEMBL9123017 | 0.78 | USP2 (0.47) | KMT2ATSHRCYP3A4 | |
| SCHEMBL1735307 | 0.78 | SCN4A (0.47) | KMT2ATSHRCYP3A4SCN4A | |
| SCHEMBL1734408 | 0.78 | KMT2A (0.41) | KMT2ATSHRTP53ALOX15ADRB2 | |
| SCHEMBL9123210 | 0.78 | KMT2A (0.41) | KMT2ATSHRTP53ALOX15ADRB2 | |
| SCHEMBL1735306 | 0.78 | KMT2A (0.41) | KMT2ATSHRTP53ALOX15ADRB2 | |
| SCHEMBL1736414 | 0.78 | KMT2A (0.41) | KMT2ATSHRTP53ALOX15ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492615-B1 | Process for producing biguanide derivative | IDEMITSU KOSAN CO (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5286905-A | Heating hydrogen halide salt of phenoxyalkylamine with dicyandiamide in paraffinic hydrocarbon solvent | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0492615-A1 | Process for producing biguanide derivative | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-07-01 | — | — | EP | disclosed |