Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | STAT6 | P42226 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10369473 | 0.85 | LMNA (0.50) | LMNAKDM4EESR1CYP3A4HIF1A | |
| SCHEMBL9125693 | 0.80 | ALDH1A1 (0.62) | LMNAKDM4EESR1CYP3A4HIF1A | |
| SCHEMBL24747286 | 0.80 | LMNA (0.64) | LMNAKDM4EESR1CYP3A4HIF1A | |
| SCHEMBL24747284 | 0.79 | LMNA (0.62) | LMNAKDM4EESR1CYP3A4HIF1A | |
| SCHEMBL9125240 | 0.79 | LMNA (0.52) | LMNAKDM4EESR1CYP3A4HIF1A | |
| SCHEMBL9125723 | 0.77 | TSHR (0.50) | LMNAKDM4EESR1CYP3A4HIF1A | |
| SCHEMBL8939673 | 0.77 | LMNA (0.50) | LMNAKDM4EESR1CYP3A4HIF1A | |
| SCHEMBL5677734 | 0.75 | LMNA (0.51) | LMNAKDM4EESR1CYP3A4HIF1A | |
| SCHEMBL12445337 | 0.74 | LMNA (0.57) | LMNAKDM4EESR1CYP3A4HIF1A | |
| SCHEMBL12521526 | 0.74 | LMNA (0.57) | LMNAKDM4EESR1CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5413997-A | For treatment of osteoporosis | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| EP-0395093-B1 | TRIPHENYLMETHANE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-5112867-A | Osteoporosis Treatment | KYOWA HAKKO GOGYO CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |