SCHEMBL9123783

SCHEMBL9123783

O=C(O)c1ccc(/C=N/S(=O)(=O)c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.56
F2 P00734 2/20 0.54
PRSS1 P07477 2/20 0.54
PRSS2 P07478 2/20 0.54
PRSS3 P35030 2/20 0.54
ALDH1A1 P00352 6/20 0.51
POLB P06746 2/20 0.50
CA2 P00918 4/20 0.48
CA1 P00915 3/20 0.48
CA12 O43570 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
CA3 P07451 1/20 0.48
CA6 P23280 1/20 0.48
CYP2C19 P33261 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9123788 1.00 KMT2A (0.56) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL9121834 0.93 CA1 (0.56) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL1933494 0.93 CA1 (0.56) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL9120473 0.93 ALDH1A1 (0.60) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL9120478 0.93 ALDH1A1 (0.60) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL9122609 0.92 ALOX15 (0.52) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL21964173 0.92 ALDH1A1 (0.62) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL21964172 0.92 ALDH1A1 (0.62) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL9123108 0.92 ALOX15 (0.52) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL1933404 0.92 ALOX15 (0.52) KMT2AF2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5463115-A Enhance bleaching action of peroxygen compounds LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1995-10-31 US claimed
EP-0446982-B1 Low-temperature bleaching compositions UNILEVER NV (NL) 1994-10-26 EP claimed
EP-0453003-B1 Bleach catalysts and compositions containing same UNILEVER NV (NL) 1994-10-05 EP claimed
EP-0453003-A2 Bleach catalysts and compositions containing same UNILEVER N.V. (NL) 1991-10-23 EP claimed
EP-0446982-A2 Low-temperature bleaching compositions UNILEVER N.V. (NL) 1991-09-18 EP claimed
US-5047163-A Low Temperature Bleaching Composition Containing A Peroxygen Compound, A Sulfonimine Oxygen Transfer Agent Activator And A! Bleach Percursor LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1991-09-10 US claimed
US-5041232-A Inlcudes peroxygen compound and surfactant LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1991-08-20 US claimed
EP-2503984-B1 SULFONIMINES AS BLEACHING ACTIVATORS HENKEL AG & CO KGAA (DE) 2017-11-08 EP disclosed
US-5463115-A Enhance bleaching action of peroxygen compounds LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1995-10-31 US disclosed
EP-0446982-B1 Low-temperature bleaching compositions UNILEVER NV (NL) 1994-10-26 EP disclosed
EP-0453003-B1 Bleach catalysts and compositions containing same UNILEVER NV (NL) 1994-10-05 EP disclosed
EP-0453003-A2 Bleach catalysts and compositions containing same UNILEVER N.V. (NL) 1991-10-23 EP disclosed
EP-0446982-A2 Low-temperature bleaching compositions UNILEVER N.V. (NL) 1991-09-18 EP disclosed
US-5047163-A Low Temperature Bleaching Composition Containing A Peroxygen Compound, A Sulfonimine Oxygen Transfer Agent Activator And A! Bleach Percursor LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1991-09-10 US disclosed
US-5041232-A Inlcudes peroxygen compound and surfactant LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1991-08-20 US disclosed