SCHEMBL1933494

SCHEMBL1933494

O=C(O)c1ccc(S(=O)(=O)/N=C/c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
KMT2A Q03164 4/20 0.53
ALDH1A1 P00352 4/20 0.53
F2 P00734 2/20 0.51
PRSS1 P07477 2/20 0.51
PRSS2 P07478 2/20 0.51
PRSS3 P35030 2/20 0.51
CA9 Q16790 2/20 0.48
CA4 P22748 1/20 0.48
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46
POLB P06746 2/20 0.46
CA12 O43570 1/20 0.46
CA3 P07451 1/20 0.46
CA6 P23280 1/20 0.46
CYP2C19 P33261 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
CA14 Q9ULX7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9121834 1.00 CA1 (0.56) CA1CA2KMT2AALDH1A1F2
SCHEMBL9120473 0.93 ALDH1A1 (0.60) CA1CA2KMT2AALDH1A1F2
SCHEMBL9120478 0.93 ALDH1A1 (0.60) CA1CA2KMT2AALDH1A1F2
SCHEMBL9123783 0.93 KMT2A (0.56) CA1CA2KMT2AALDH1A1F2
SCHEMBL9123788 0.93 KMT2A (0.56) CA1CA2KMT2AALDH1A1F2
SCHEMBL1933404 0.86 ALOX15 (0.52) CA1CA2KMT2AALDH1A1F2
SCHEMBL21964172 0.86 ALDH1A1 (0.62) CA1CA2KMT2AALDH1A1F2
SCHEMBL21964173 0.86 ALDH1A1 (0.62) CA1CA2KMT2AALDH1A1F2
SCHEMBL9122609 0.86 ALOX15 (0.52) CA1CA2KMT2AALDH1A1F2
SCHEMBL9123108 0.86 ALOX15 (0.52) CA1CA2KMT2AALDH1A1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8323356-B2 Sulfonimines as bleaching activators HENKEL AG & CO. KGAA (DE) 2012-12-04 US claimed
US-20120227756-A1 SULFONIMINES AS BLEACHING ACTIVATORS HENKEL AG & CO. KGAA (DE) 2012-09-13 US claimed
US-5463115-A Enhance bleaching action of peroxygen compounds LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1995-10-31 US claimed
EP-0446982-B1 Low-temperature bleaching compositions UNILEVER NV (NL) 1994-10-26 EP claimed
EP-0453003-B1 Bleach catalysts and compositions containing same UNILEVER NV (NL) 1994-10-05 EP claimed
EP-0453003-A2 Bleach catalysts and compositions containing same UNILEVER N.V. (NL) 1991-10-23 EP claimed
US-5047163-A Low Temperature Bleaching Composition Containing A Peroxygen Compound, A Sulfonimine Oxygen Transfer Agent Activator And A! Bleach Percursor LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1991-09-10 US claimed
US-5041232-A Inlcudes peroxygen compound and surfactant LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1991-08-20 US claimed
EP-2503984-B1 SULFONIMINES AS BLEACHING ACTIVATORS HENKEL AG & CO KGAA (DE) 2017-11-08 EP disclosed
US-8323356-B2 Sulfonimines as bleaching activators HENKEL AG & CO. KGAA (DE) 2012-12-04 US disclosed
EP-2503984-A1 SULFONIMINES AS BLEACHING ACTIVATORS Henkel AG & Co. KGaA (DE) 2012-10-03 EP disclosed
US-20120227756-A1 SULFONIMINES AS BLEACHING ACTIVATORS HENKEL AG & CO. KGAA (DE) 2012-09-13 US disclosed
WO-2011064007-A1 SULFONIMINES AS BLEACHING ACTIVATORS HENKEL AG & CO. KGAA (DE) 2011-06-03 WO disclosed
US-5463115-A Enhance bleaching action of peroxygen compounds LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1995-10-31 US disclosed
EP-0446982-B1 Low-temperature bleaching compositions UNILEVER NV (NL) 1994-10-26 EP disclosed
EP-0453003-B1 Bleach catalysts and compositions containing same UNILEVER NV (NL) 1994-10-05 EP disclosed
EP-0453003-A2 Bleach catalysts and compositions containing same UNILEVER N.V. (NL) 1991-10-23 EP disclosed
EP-0446982-A2 Low-temperature bleaching compositions UNILEVER N.V. (NL) 1991-09-18 EP disclosed
US-5047163-A Low Temperature Bleaching Composition Containing A Peroxygen Compound, A Sulfonimine Oxygen Transfer Agent Activator And A! Bleach Percursor LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1991-09-10 US disclosed
US-5041232-A Inlcudes peroxygen compound and surfactant LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1991-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120227756-A1 SULFONIMINES AS BLEACHING ACTIVATORS KRT18, SQOR, GPX4 CA1 1383/4885CA2 576/4885KMT2A 430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.