Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118908 | 0.86 | — | — | |
| SCHEMBL27820284 | 0.82 | — | — | |
| SCHEMBL434403 | 0.81 | LMNA (0.32) | LMNA | |
| SCHEMBL9120551 | 0.80 | OPRM1 (0.30) | OPRM1 | |
| SCHEMBL1069100 | 0.80 | NFKB1 (0.30) | — | |
| SCHEMBL29201586 | 0.77 | LMNA (0.31) | LMNA | |
| SCHEMBL7630668 | 0.77 | LMNA (0.31) | LMNA | |
| SCHEMBL2336574 | 0.75 | — | — | |
| Isopropylamine SCHEMBL28749140 | 0.74 | LMNA (0.48) | OPRM1LMNASPHK1 | |
| SCHEMBL8569531 | 0.74 | OPRM1 (0.32) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385961-A | Coating aminofunctional polysiloxane over solid phosphite core; nonhydrolyzing | GENERAL ELECTRIC COMPANY (US) | 1995-01-31 | — | — | US | disclosed |
| EP-0609034-A1 | Amino silicone/phosphite compositions | GENERAL ELECTRIC COMPANY (US) | 1994-08-03 | — | — | EP | disclosed |
| US-4496705-A | TREATING POLYSILOXANE WITH ORGANO-SULTONE | GENERAL ELECTRIC COMPANY (US) | 1985-01-29 | — | — | US | disclosed |