Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TGM2 | P21980 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 4/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23199033 | 0.78 | TDP1 (0.54) | TDP1TGM2BTKEGFRTRPV1 | |
| SCHEMBL9123180 | 0.75 | TDP1 (0.47) | TDP1TGM2RXFP1BTKEGFR | |
| SCHEMBL390106 | 0.73 | TDP1 (0.64) | TDP1RXFP1EGFRTRPV1NLRP3 | |
| SCHEMBL9126517 | 0.69 | TDP1 (0.41) | TDP1TGM2RXFP1BTKEGFR | |
| SCHEMBL5078546 | 0.69 | TDP1 (0.51) | TDP1RXFP1EGFRNLRP3JAK3 | |
| SCHEMBL1098272 | 0.69 | TDP1 (0.79) | TDP1RXFP1EGFRERBB2POLB | |
| SCHEMBL27823783 | 0.68 | TDP1 (0.64) | TDP1TGM2RXFP1EGFRJAK3 | |
| SCHEMBL18100115 | 0.67 | TGM2 (0.58) | TGM2BTKEGFRITKTRPV1 | |
| SCHEMBL30935191 | 0.67 | TGM2 (0.61) | TGM2BTKEGFRTRPV1NLRP3 | |
| SCHEMBL235432 | 0.67 | TGM2 (0.61) | TGM2BTKEGFRTRPV1NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478575-A | Polymers having benzeneboronic acid groups and insulin complexes of same of a sugar response type | NIPPON OIL & FATS CO., LTD. (JP) | 1995-12-26 | — | — | US | claimed |
| EP-0424168-B1 | POLYMER COMPLEXES OF A SUGAR RESPONSE TYPE | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1993-09-01 | — | — | EP | claimed |