SCHEMBL390106

SCHEMBL390106

C=C(C)C(=O)Nc1cccc(B(O)O)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.64
NLRP3 Q96P20 1/20 0.50
TRPV1 Q8NER1 1/20 0.47
RXFP1 Q9HBX9 1/20 0.45
GPR35 Q9HC97 1/20 0.44
ESRRG P62508 4/20 0.44
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
POLB P06746 1/20 0.43
RECQL P46063 1/20 0.43
BLM P54132 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
JAK3 P52333 4/20 0.43
EGFR P00533 1/20 0.42
ERBB2 P04626 1/20 0.42
PDE3B Q13370 1/20 0.41
PDE3A Q14432 1/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23199033 0.90 TDP1 (0.54) TDP1NLRP3TRPV1ESRRGESR1
SCHEMBL1098272 0.84 TDP1 (0.79) TDP1RXFP1GPR35ALDH1A1KDM4E
SCHEMBL8930 0.83 ALDH1A1 (0.59) NLRP3TRPV1ESRRGESR1ESR2
SCHEMBL1370185 0.80 TRPV1 (0.47) TDP1NLRP3TRPV1GPR35ESRRG
SCHEMBL7779085 0.80 TDP1 (0.68) TDP1KDM4EJAK3
SCHEMBL5078546 0.80 TDP1 (0.51) TDP1NLRP3RXFP1GPR35ALDH1A1
SCHEMBL11349846 0.80 TRPV1 (0.51) NLRP3TRPV1GPR35ESRRGESR1
SCHEMBL1726459 0.80 RXFP1 (0.59) TDP1TRPV1RXFP1ALDH1A1KDM4E
SCHEMBL5421444 0.78 TDP1 (1.00) TDP1ALDH1A1POLBL3MBTL1CYP1A2
SCHEMBL8477048 0.78 TDP1 (0.70) TDP1RXFP1ALDH1A1JAK3CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079321-A Composite flocculant for tea filter paper making wastewater and preparation method thereof 2026-05-26 CN claimed
US-12595396-B2 Acid resistant filter media ENTEGRIS, INC. (US) 2026-04-07 US claimed
EP-3927236-B1 MEDIATION OF IN VIVO ANALYTE SIGNAL DEGRADATION SENSEONICS INC (US) 2025-08-27 EP claimed
EP-4599224-A1 RAPID GELLING AQUEOUS MOUNTING MEDIA Life Technologies Corporation (US) 2025-08-13 EP claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-119463025-B Preparation method of thermochromic self-repairing gel and application of thermochromic self-repairing gel in intelligent window 深地科学与工程云龙湖实验室 2025-05-09 CN claimed
CN-118792898-B Short-process polyester color fixing process 绍兴市高峰印染有限公司 2025-05-02 CN claimed
CN-119912221-A Weather-resistant decorative water-based polyurethane mortar color sand self-leveling floor material 缤狮材料科技(上海)有限公司 2025-05-02 CN claimed
US-12279862-B2 Mediation of in vivo analyte signal degradation SENSEONICS, INCORPORATED (US) 2025-04-22 US claimed
US-20070027266-A1 Oxidizing one or more thiocarbonylthio ends of a polymer resulting from a radical polymerization controlled by reversible addition-fragmentation using thiocarbonylthio by reacting with ozone SPECIALTY OPERATIONS FRANCE (FR) 2007-02-01 US claimed
US-20060106178-A1 Synthesis of statistical microgels by means of controlled radical polymerisation RHODIA CHIMIE (FR) 2006-05-18 US claimed
US-20050203256-A1 Poymer obtained by means of controlled radical polymerisation comprising at least one boronate function, association thereof with a ligand compound and uses of same RHODIA CHIMIE (FR) 2005-09-15 US claimed
US-20040248326-A1 Hydrogel compositions, devices, and microscale components REGENTS OF THE UNIVERSITY OF MINNESOTA 2004-12-09 US claimed
US-6751491-B2 BIOSENSOR SYSTEM INCLUDING IMPLANTABLE ANALYTE-SENSITIVE HYDROGEL SLAB, DISPLACEMENT VOLUME OF WHICH VARIES WITH CHANGES IN CONCENTRATION OF ANALYTE IN BODY FLUID, SCANNING MEANS QUANTIFIABLY DETECTING CHANGES BY CAPTURING SLAB IMAGE GENSEN TECHNOLOGIES, INC. 2004-06-15 US claimed
WO-2003051286-A2 HYDROGEL COMPOSITIONS, DEVICES, AND MICROSCALE COMPONENTS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2003-06-26 WO claimed
US-20030100822-A1 Analyte measuring biosensor chip using image scanning system GENSEN TECHNOLOGIES, INC. 2003-05-29 US claimed
US-5478575-A Polymers having benzeneboronic acid groups and insulin complexes of same of a sugar response type NIPPON OIL & FATS CO., LTD. (JP) 1995-12-26 US claimed
EP-0424168-B1 POLYMER COMPLEXES OF A SUGAR RESPONSE TYPE NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1993-09-01 EP claimed
EP-0424168-A1 Polymer complexes of a sugar response type NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-04-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12279862-B2 Mediation of in vivo analyte signal degradation SLC2A1, SLC2A4, SLC2A3 TDP1 3445/4885NLRP3 1102/4885TRPV1 2270/4885
US-12595396-B2 Acid resistant filter media SDC2, F7, SDC1 TDP1 2343/4885NLRP3 4677/4885TRPV1 277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.