Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 3/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12146331 | 0.85 | MEN1 (0.56) | MEN1KMT2ALMNAMAPTTHRB | |
| SCHEMBL16249237 | 0.84 | MEN1 (0.38) | MEN1KMT2ALMNAMAPTTHRB | |
| SCHEMBL12713792 | 0.83 | HTT (0.40) | MEN1KMT2ALMNAMAPTTHRB | |
| SCHEMBL3859355 | 0.83 | MEN1 (0.41) | MEN1KMT2ALMNAMAPTTHRB | |
| SCHEMBL14457767 | 0.83 | MEN1 (0.41) | MEN1KMT2ALMNAMAPTTHRB | |
| SCHEMBL2361662 | 0.83 | MEN1 (0.41) | MEN1KMT2ALMNAMAPTTHRB | |
| SCHEMBL29726657 | 0.83 | MEN1 (0.41) | MEN1KMT2ALMNAMAPTTHRB | |
| SCHEMBL10138057 | 0.83 | MEN1 (0.41) | MEN1KMT2ALMNAMAPTTHRB | |
| SCHEMBL12201419 | 0.82 | MEN1 (0.35) | MEN1KMT2ALMNAMAPTTHRB | |
| SCHEMBL559842 | 0.82 | LMNA (0.40) | MEN1KMT2ALMNAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397690-A | Near-infrared absorbing dyes prepared from stenhouse salts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0591820-A1 | Near-infrared absorbing dyes prepared from Stenhouse salts | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-04-13 | — | — | EP | disclosed |