Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15293516 | 0.86 | MAPT (0.44) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL9124332 | 0.84 | MEN1 (0.39) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL12934507 | 0.84 | HTT (0.42) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL19052148 | 0.82 | MEN1 (0.36) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL13223583 | 0.80 | MEN1 (0.42) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL1656985 | 0.80 | MEN1 (0.42) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL5271477 | 0.79 | MEN1 (0.41) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL5271474 | 0.79 | MEN1 (0.41) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL721215 | 0.79 | MEN1 (0.41) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL135011 | 0.79 | LMNA (0.41) | MEN1LMNAMAPTTHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170183501-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-06-29 | — | — | US | disclosed |
| US-9441270-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-09-13 | — | — | US | disclosed |
| US-20150072894-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-03-12 | — | — | US | disclosed |
| US-8889886-B2 | Cyanine dyes | PACIFIC BIOSCIENCES, INC. (US) | 2014-11-18 | — | — | US | disclosed |