Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 2/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | LAP3 | P28838 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15397422 | 0.77 | ALDH1A1 (0.65) | ALDH1A1TDP1L3MBTL1CYP3A4TSHR | |
| SCHEMBL5836722 | 0.77 | HTT (0.57) | ALDH1A1TDP1L3MBTL1CYP3A4TSHR | |
| SCHEMBL11467759 | 0.76 | LTA4H (0.56) | L3MBTL1NR4A1NR4A2NR4A3PRKCA | |
| SCHEMBL11252632 | 0.76 | LTA4H (0.56) | L3MBTL1NR4A1NR4A2NR4A3PRKCA | |
| SCHEMBL824976 | 0.76 | LMNA (0.64) | L3MBTL1NR4A1NR4A2NR4A3GAA | |
| SCHEMBL2032112 | 0.76 | LMNA (0.64) | L3MBTL1NR4A1NR4A2NR4A3GAA | |
| SCHEMBL7761599 | 0.75 | NR4A1 (0.62) | NR4A1NR4A2NR4A3ALOX5MAOB | |
| SCHEMBL50807 | 0.75 | KMT2A (0.73) | ALDH1A1TDP1L3MBTL1NR4A1NR4A2 | |
| SCHEMBL9121818 | 0.75 | LMNA (0.51) | L3MBTL1NR4A1NR4A2NR4A3PRKCA | |
| SCHEMBL21755634 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TDP1L3MBTL1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5413997-A | For treatment of osteoporosis | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| EP-0395093-B1 | TRIPHENYLMETHANE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-5112867-A | Osteoporosis Treatment | KYOWA HAKKO GOGYO CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0395093-A1 | Triphenylmethane derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |