Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11000264 | 0.95 | MAOB (0.58) | MAOBMAOAMEN1POLBMAPK1 | |
| SCHEMBL24533732 | 0.87 | RXRA (0.58) | APPFFAR1RXRARXRB | |
| SCHEMBL9121973 | 0.84 | ACACB (0.60) | MAOBFFAR1 | |
| SCHEMBL15132940 | 0.84 | RXRA (0.64) | MAOBMAOAMEN1POLBMAPK1 | |
| SCHEMBL10722524 | 0.84 | RXRA (0.64) | MAOBMAOAMEN1POLBMAPK1 | |
| Biphenyl SCHEMBL9839827 | 0.83 | ACACB (0.59) | FFAR1 | |
| SCHEMBL9547782 | 0.81 | MAOB (0.57) | MAOBMAOAMEN1POLBMAPK1 | |
| SCHEMBL9126010 | 0.80 | NR5A1 (0.53) | MEN1KMT2ARXRARXRBMMP9 | |
| SCHEMBL11308298 | 0.80 | ADRB2 (0.50) | MAPK1FFAR1 | |
| SCHEMBL11753634 | 0.80 | MAOB (0.58) | MAOBMAOAMEN1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447659-A | Hydrolysis of the ester derivative with esterase to form the alcohol | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-09-05 | — | — | US | disclosed |
| US-5338484-A | Optically active benzene derivatives, process for producing the same and liquid-crystalline substances containing said derivatives as active ingredient and optical switching elements | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-08-16 | — | — | US | disclosed |
| US-5274168-A | Optically active benzene derivatives, process for producing the same and liquid-crystalline substances containing said derivatives as active ingredient and optical switching elements | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-12-28 | — | — | US | disclosed |
| EP-0288297-B1 | OPTICALLY ACTIVE BENZENE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-03-17 | — | — | EP | disclosed |
| EP-0284371-B1 | NOVEL OPTICALLY ACTIVE BENZENE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND LIQUID-CRYSTALLINE SUBSTANCES CONTAINING SAID DERIVATIVES AS ACTIVE INGREDIENT AND OPTICAL SWITCHING ELEMENTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-5002693-A | Novel optically active benzene derivatives, process for producing the same and liquid-crystalline substances containing said derivatives as active ingredient and optical switching elements | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-03-26 | — | — | US | disclosed |
| US-4985590-A | Optically active benzene derivatives and process for preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-01-15 | — | — | US | disclosed |