SCHEMBL24533732

SCHEMBL24533732

CC(O)c1ccc(OCc2ccc(COc3ccc(C(C)O)cc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.58
RXRB P28702 1/20 0.58
APP P05067 5/20 0.50
ALOX5 P09917 1/20 0.48
FFAR1 O14842 1/20 0.48
PARP10 Q53GL7 1/20 0.47
F2 P00734 1/20 0.47
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
PRSS3 P35030 1/20 0.47
TMPRSS6 Q8IU80 1/20 0.47
ST14 Q9Y5Y6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11000264 0.91 MAOB (0.58) RXRARXRBAPPFFAR1
SCHEMBL1497960 0.91 LMNA (0.61) RXRARXRBALOX5
SCHEMBL6743494 0.88 RXRA (0.49) RXRARXRBAPPALOX5FFAR1
SCHEMBL9124643 0.87 MAOB (0.54) RXRARXRBAPPFFAR1
SCHEMBL9121973 0.86 ACACB (0.60) ALOX5FFAR1
Biphenyl SCHEMBL9839827 0.85 ACACB (0.59) ALOX5FFAR1
SCHEMBL13160063 0.83 RXRA (0.72) RXRARXRBAPP
SCHEMBL12279053 0.83 RXRA (0.72) RXRARXRBAPP
SCHEMBL9126010 0.82 NR5A1 (0.53) RXRARXRB
SCHEMBL17602110 0.81 ALOX5 (0.53) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4258056-A2 ALCOHOL COMPOUND, CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-11 EP disclosed
US-20220197140-A1 ALCOHOL COMPOUND, CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-06-23 US disclosed