Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122348 | 0.87 | ALDH1A1 (0.51) | KMT2AGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9124217 | 0.86 | ALDH1A1 (0.56) | KMT2AGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9124992 | 0.86 | ALDH1A1 (0.56) | KMT2AGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9123908 | 0.86 | ALDH1A1 (0.56) | KMT2AGAAALDH1A1TDP1HTT | |
| SCHEMBL9124250 | 0.84 | ALDH1A1 (0.62) | KMT2AGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9126910 | 0.82 | HTT (0.51) | KMT2AGAAALDH1A1SMN1; SMN2GLA | |
| SCHEMBL9125231 | 0.82 | KMT2A (0.57) | KMT2AALDH1A1SMN1; SMN2GLAHTT | |
| SCHEMBL9123049 | 0.81 | ALDH1A1 (0.54) | KMT2AGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9124615 | 0.81 | MAPT (0.57) | KMT2AGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9122324 | 0.81 | LMNA (0.54) | KMT2AGAAALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5413997-A | For treatment of osteoporosis | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| EP-0395093-B1 | TRIPHENYLMETHANE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-5112867-A | Osteoporosis Treatment | KYOWA HAKKO GOGYO CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0395093-A1 | Triphenylmethane derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |