Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2707925 | 0.81 | POLB (0.43) | CASP1POLBCASP3CYP1A2EHMT2 | |
| SCHEMBL9342906 | 0.80 | CASP1 (0.40) | CASP1POLBCASP3CYP1A2EHMT2 | |
| SCHEMBL8730348 | 0.77 | MEN1 (0.41) | CASP1POLBCASP3CYP1A2EHMT2 | |
| SCHEMBL1961000 | 0.77 | KMT2A (0.41) | CASP1POLBCASP3CYP1A2EHMT2 | |
| SCHEMBL9549241 | 0.77 | CASP1 (0.38) | CASP1POLBCASP3CYP1A2EHMT2 | |
| SCHEMBL9190585 | 0.75 | POLB (0.46) | POLBCASP3CYP1A2EHMT2EHMT1 | |
| SCHEMBL31288119 | 0.72 | DPP4 (0.40) | CASP1POLBCASP3CYP1A2EHMT2 | |
| SCHEMBL5940982 | 0.71 | MEN1 (0.43) | POLBCASP3CYP1A2EHMT2EHMT1 | |
| SCHEMBL30472938 | 0.71 | CASP3 (0.46) | POLBCASP3CYP1A2EHMT2EHMT1 | |
| SCHEMBL2156119 | 0.71 | CASP3 (0.46) | POLBCASP3CYP1A2EHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449740-A | Resin systems derived from insitu-generated bisdienes from bis-benzocyclobutene compounds | THE UNIVERSITY OF DAYTON (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0402632-A2 | Aromatic polyimide silanol compounds, precursors and polymers thereof | Hughes Aircraft Company (US) | 1990-12-19 | — | — | EP | disclosed |
| US-4864047-A | Aminophenoxyphosphazenes and process for producing same | THE DOW CHEMICAL COMPANY (US) | 1989-09-05 | — | — | US | disclosed |
| US-4745206-A | Aminophenoxyphosphazenes and a process for producing same | THE DOW CHEMICAL COMPANY (US) | 1988-05-17 | — | — | US | disclosed |