Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125334 | 0.77 | CASP1 (0.41) | CASP1POLBCASP3CYP1A2EHMT2 | |
| SCHEMBL2707925 | 0.76 | POLB (0.43) | CASP1POLBCASP3CYP1A2EHMT2 | |
| SCHEMBL9342906 | 0.75 | CASP1 (0.40) | CASP1POLBCASP3CYP1A2EHMT2 | |
| SCHEMBL1961000 | 0.72 | KMT2A (0.41) | CASP1POLBCASP3CYP1A2EHMT2 | |
| SCHEMBL8730348 | 0.72 | MEN1 (0.41) | CASP1POLBCASP3CYP1A2EHMT2 | |
| SCHEMBL9190585 | 0.71 | POLB (0.46) | POLBCASP3CYP1A2EHMT2EHMT1 | |
| SCHEMBL31288119 | 0.68 | DPP4 (0.40) | CASP1POLBCASP3CYP1A2EHMT2 | |
| SCHEMBL5940982 | 0.67 | MEN1 (0.43) | POLBCASP3CYP1A2EHMT2EHMT1 | |
| SCHEMBL30472938 | 0.67 | CASP3 (0.46) | POLBCASP3CYP1A2EHMT2EHMT1 | |
| SCHEMBL2156119 | 0.67 | CASP3 (0.46) | POLBCASP3CYP1A2EHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5274135-A | Aminating in the presence of a metal-containing catalyst | THE DOW CHEMICAL COMPANY (US) | 1993-12-28 | — | — | US | disclosed |