Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6557727 | 0.89 | HTR6 (0.42) | HTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7940229 | 0.85 | HTR6 (0.35) | HTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7940238 | 0.80 | — | — | |
| SCHEMBL29554562 | 0.76 | HTR6 (0.53) | HTR6SIGMAR1 | |
| SCHEMBL1539616 | 0.76 | HTR6 (0.53) | HTR6SIGMAR1 | |
| SCHEMBL29821974 | 0.74 | HTR6 (0.51) | HTR6SIGMAR1 | |
| SCHEMBL20944811 | 0.74 | HTR6 (0.51) | HTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7939285 | 0.73 | CYP1A2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL8580574 | 0.73 | TNK2 (0.31) | HTR6 | |
| Hydrochloric Acid SCHEMBL7931277 | 0.72 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672675-A1 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5451649-A | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-09-19 | — | — | US | disclosed |