Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 18/20 | 0.60 |
| ▸ | PPIF | P30405 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783281 | 0.88 | PPIA (0.72) | PPIAPPIF | |
| SCHEMBL9125643 | 0.87 | PPIA (0.60) | PPIAPPIF | |
| SCHEMBL9125073 | 0.85 | PPIA (0.75) | PPIAPPIF | |
| SCHEMBL9126107 | 0.82 | PPIA (0.77) | PPIAPPIF | |
| SCHEMBL9357577 | 0.81 | PPIA (0.60) | PPIAPPIF | |
| SCHEMBL9125085 | 0.81 | PPIA (0.68) | PPIAPPIF | |
| SCHEMBL9125802 | 0.80 | PPIA (0.58) | PPIAPPIF | |
| SCHEMBL9128497 | 0.80 | PPIA (0.60) | PPIAPPIF | |
| SCHEMBL9125727 | 0.78 | PPIA (0.56) | PPIAPPIFMAOB | |
| SCHEMBL9122331 | 0.76 | PPIA (0.61) | PPIAPPIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409943-A | [(alkoxy)pyridinyl]amine compounds which are useful in the treatment of gastrointestinal disorders | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1995-04-25 | — | — | US | disclosed |
| EP-0625143-A1 | PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993015055-A1 | PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-08-05 | — | — | WO | disclosed |