SCHEMBL9126352

SCHEMBL9126352

CN(C)CCN1CCCN(CCN(C)C)C1=O

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
PTK2B Q14289 1/20 0.41
ESR2 Q92731 1/20 0.41
DAO P14920 1/20 0.36
TERT O14746 2/20 0.33
DRD2 P14416 4/20 0.33
DRD3 P35462 4/20 0.33
KCNH2 Q12809 4/20 0.33
HEXA P06865 1/20 0.33
HEXB P07686 1/20 0.33
SLC6A4 P31645 1/20 0.32
HRH1 P35367 1/20 0.32
PIK3CD O00329 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12311474 0.90 PER2 (0.38) KDM4EALDH1A1LMNAMAPTPTK2B
SCHEMBL20912198 0.83 KDM4E (0.39) KDM4EALDH1A1LMNAMAPTPTK2B
SCHEMBL9123420 0.81 KDM4E (0.40) KDM4EALDH1A1LMNAMAPTPTK2B
SCHEMBL13893014 0.79 PIK3CD (0.50) KDM4EALDH1A1LMNAMAPTPTK2B
SCHEMBL22604309 0.77 BCHE (0.42)
SCHEMBL10264989 0.76 L3MBTL1 (0.45) KDM4EALDH1A1LMNAMAPTPTK2B
Hydrochloric Acid SCHEMBL8927739 0.76 KDM4E (0.37) KDM4EALDH1A1LMNAMAPTPTK2B
SCHEMBL25065916 0.75 DPP4 (0.37) KDM4EALDH1A1LMNAMAPTPTK2B
Hydrochloric Acid SCHEMBL319484 0.75 L3MBTL1 (0.44) KDM4EALDH1A1LMNAMAPTPTK2B
SCHEMBL12872479 0.75 PER2 (0.40) KDM4EALDH1A1LMNAMAPTPTK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5413627-A Scrubbing with saturated or unsaturated heterocyclic nitrogen compound, amine, amide, urea, hydrazine, hydrazide, hydrazone functional groups LINDE AKTIENGESELLSCHAFT (DE) 1995-05-09 US claimed
EP-0550454-B1 PROCESS FOR THE SELECTIVE REMOVAL OF INORGANIC AND/OR ORGANIC SULPHUR COMPOUNDS FROM GASES LINDE AG (DE) 1995-01-25 EP claimed
EP-0550454-A1 PROCESS FOR THE SELECTIVE REMOVAL OF INORGANIC AND/OR ORGANIC SULPHUR COMPOUNDS FROM GASES. LINDE AG (DE) 1993-07-14 EP claimed
WO-1992004102-A1 PROCESS FOR THE SELECTIVE REMOVAL OF INORGANIC AND/OR ORGANIC SULPHUR COMPOUNDS FROM GASES LINDE AKTIENGESELLSCHAFT (DE) 1992-03-19 WO claimed
US-20090181948-A1 DIAMINE DERIVATIVE KYOWA HAKKO KOGYO CO., LTD. (JP) 2009-07-16 US disclosed
US-20090181948-A1 DIAMINE DERIVATIVE KYOWA HAKKO KOGYO CO., LTD. (JP) 2009-07-16 US disclosed
EP-1847530-A1 DIAMINE DERIVATIVE KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-10-24 EP disclosed
US-5413627-A Scrubbing with saturated or unsaturated heterocyclic nitrogen compound, amine, amide, urea, hydrazine, hydrazide, hydrazone functional groups LINDE AKTIENGESELLSCHAFT (DE) 1995-05-09 US disclosed
EP-0550454-B1 PROCESS FOR THE SELECTIVE REMOVAL OF INORGANIC AND/OR ORGANIC SULPHUR COMPOUNDS FROM GASES LINDE AG (DE) 1995-01-25 EP disclosed
EP-0550454-A1 PROCESS FOR THE SELECTIVE REMOVAL OF INORGANIC AND/OR ORGANIC SULPHUR COMPOUNDS FROM GASES. LINDE AG (DE) 1993-07-14 EP disclosed
WO-1992004102-A1 PROCESS FOR THE SELECTIVE REMOVAL OF INORGANIC AND/OR ORGANIC SULPHUR COMPOUNDS FROM GASES LINDE AKTIENGESELLSCHAFT (DE) 1992-03-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090181948-A1 DIAMINE DERIVATIVE ARG1, PRMT5, PRMT1 KDM4E 418/4885ALDH1A1 395/4885LMNA 3566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.