Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HNF4A | P41235 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333023 | 0.92 | TDP1 (0.69) | LMNATDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL5834916 | 0.88 | ALDH1A1 (0.68) | LMNATDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL537056 | 0.86 | LMNA (0.70) | LMNATDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL18745914 | 0.85 | LMNA (0.56) | LMNATDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL14059325 | 0.84 | TDP1 (0.61) | LMNATDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL21027553 | 0.84 | TDP1 (0.58) | LMNATDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL26799644 | 0.84 | TDP1 (0.58) | LMNATDP1KMT2ASLC6A2SLC6A3 | |
| Benzyl Benzoate SCHEMBL19138878 | 0.83 | TDP1 (0.73) | LMNATDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL2580214 | 0.83 | TDP1 (0.66) | LMNATDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL2984951 | 0.82 | TDP1 (0.60) | LMNATDP1KMT2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468897-A | Bi-aromatic esters, a process for their preparation and their use in human or veterinary medicine and in cosmetic compositions | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1995-11-21 | — | — | US | disclosed |
| US-5332856-A | Treatment of a dermatologic, rheumatismal, respiratory or ophthalmologic ailment | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1994-07-26 | — | — | US | disclosed |
| US-5200550-A | Administering for dermatologic, rheumatismal, respiratory or ophthalomologic disorders | CENTRE INTERNATIONAL DE RECHERCES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1993-04-06 | — | — | US | disclosed |