Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | EP300 | Q09472 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14545166 | 0.89 | ALDH1A1 (0.56) | LMNAALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL11798186 | 0.79 | ALDH1A1 (0.62) | LMNAALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL8652532 | 0.78 | LMNA (0.54) | LMNAALDH1A1CYP3A4CA2EP300 | |
| SCHEMBL8651105 | 0.76 | ALDH1A1 (0.55) | LMNAALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL25698136 | 0.76 | ALDH1A1 (0.58) | LMNAALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL8602691 | 0.76 | LMNA (0.54) | LMNAALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL1835542 | 0.75 | LMNA (0.53) | LMNAALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL13431874 | 0.75 | ALDH1A1 (0.53) | LMNAALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL17912855 | 0.75 | LMNA (0.51) | LMNAALDH1A1CYP3A4CA2EP300 | |
| SCHEMBL8602437 | 0.74 | LMNA (0.52) | LMNAALDH1A1CYP3A4CA2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524419-B1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS (JP) | 1995-09-06 | — | — | EP | disclosed |
| US-5391806-A | A storage stable chromogens as color-developing agent or stabilizers | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5270281-A | Chromogenic compound | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0524419-A1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-27 | — | — | EP | disclosed |