Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.81 |
| ▸ | TBXAS1 | P24557 | 9/20 | 0.56 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128291 | 0.89 | F2 (1.00) | F2TBXAS1PLGTBXA2R | |
| SCHEMBL9129291 | 0.89 | F2 (0.64) | F2TBXAS1TBXA2R | |
| SCHEMBL9127309 | 0.88 | F2 (0.83) | F2PLGTBXA2R | |
| SCHEMBL9128713 | 0.83 | F2 (0.74) | F2TBXAS1PLGTBXA2RKDM4E | |
| SCHEMBL9130373 | 0.83 | TBXAS1 (0.59) | TBXAS1TBXA2R | |
| SCHEMBL9484732 | 0.81 | F2 (0.57) | F2TBXAS1PLGTBXA2RKDM4E | |
| SCHEMBL9128576 | 0.80 | F2 (0.67) | F2TBXAS1PLGTBXA2R | |
| SCHEMBL9126951 | 0.80 | F2 (0.69) | F2TBXAS1PLGTBXA2R | |
| SCHEMBL9129898 | 0.79 | F2 (0.68) | F2PLGTBXA2R | |
| Hydrochloric Acid SCHEMBL9132077 | 0.79 | F2 (0.68) | F2TBXAS1PLGTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0564499-B1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0564499-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-13 | — | — | EP | disclosed |
| WO-1992011234-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-07-09 | — | — | WO | disclosed |