Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 16/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 14/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129291 | 0.90 | F2 (0.64) | TBXAS1TBXA2RMEN1KMT2ANAMPT | |
| SCHEMBL9128640 | 0.85 | F2 (0.66) | TBXAS1TBXA2RMEN1KMT2APRMT1 | |
| SCHEMBL10836333 | 0.85 | TBXAS1 (0.71) | TBXAS1TBXA2RPRMT1 | |
| SCHEMBL9485381 | 0.84 | TBXAS1 (0.58) | TBXAS1TBXA2RMEN1KMT2ANAMPT | |
| SCHEMBL9128802 | 0.83 | F2 (0.81) | TBXAS1TBXA2R | |
| SCHEMBL9207918 | 0.81 | TBXAS1 (0.73) | TBXAS1TBXA2R | |
| SCHEMBL9754552 | 0.80 | MEN1 (0.84) | TBXA2RMEN1KMT2APRMT1 | |
| SCHEMBL9754483 | 0.78 | MEN1 (0.75) | TBXA2RMEN1KMT2APRMT1 | |
| SCHEMBL9128371 | 0.77 | KMT2A (0.59) | TBXA2RMEN1KMT2APRMT1 | |
| SCHEMBL1287281 | 0.76 | PRMT1 (0.83) | TBXA2RMEN1KMT2APRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0564499-B1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0564499-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-13 | — | — | EP | disclosed |
| WO-1992011234-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-07-09 | — | — | WO | disclosed |