Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.64 |
| ▸ | TBXAS1 | P24557 | 12/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 9/20 | 0.52 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130373 | 0.90 | TBXAS1 (0.59) | TBXAS1TBXA2RNAMPTMEN1KMT2A | |
| SCHEMBL9128802 | 0.89 | F2 (0.81) | F2TBXAS1TBXA2R | |
| SCHEMBL9129703 | 0.88 | F2 (0.78) | F2TBXAS1TBXA2RSGMS1TSHR | |
| SCHEMBL9131485 | 0.82 | F2 (0.58) | F2TBXAS1TBXA2RSGMS1HTT | |
| SCHEMBL9128291 | 0.78 | F2 (1.00) | F2TBXAS1TBXA2R | |
| SCHEMBL10836333 | 0.78 | TBXAS1 (0.71) | TBXAS1TBXA2R | |
| SCHEMBL9128346 | 0.78 | SGMS1 (0.57) | F2TBXAS1TBXA2RSGMS1SMN1; SMN2 | |
| SCHEMBL9128700 | 0.77 | MEN1 (0.65) | F2TBXAS1TBXA2RSGMS1SMN1; SMN2 | |
| SCHEMBL9485381 | 0.77 | TBXAS1 (0.58) | TBXAS1TBXA2RNAMPTADRB2ADRB1 | |
| SCHEMBL9129452 | 0.76 | MEN1 (0.58) | F2TBXA2RSGMS1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0564499-B1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0564499-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-13 | — | — | EP | disclosed |
| WO-1992011234-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-07-09 | — | — | WO | disclosed |