SCHEMBL9128805

SCHEMBL9128805

CC(C)(C)c1cc(COc2ccccc2)cc(C(C)(C)C)c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
GAA P10253 3/20 0.51
LMNA P02545 3/20 0.49
CYP1A2 P05177 3/20 0.49
HIF1A Q16665 3/20 0.49
CYP2C19 P33261 2/20 0.49
PTGS1 P23219 1/20 0.49
SLC6A2 P23975 1/20 0.49
PTGS2 P35354 1/20 0.49
SLC6A3 Q01959 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
ALDH1A1 P00352 4/20 0.46
TSHR P16473 3/20 0.46
CA2 P00918 3/20 0.46
CA1 P00915 2/20 0.46
BLM P54132 3/20 0.45
CYP3A4 P08684 2/20 0.45
MAPK1 P28482 2/20 0.45
ATM Q13315 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14000562 0.90 HSPA5 (0.56) MEN1KMT2AGAALMNACYP1A2
SCHEMBL6543866 0.84 ALDH1A1 (0.44) MEN1KMT2AGAALMNACYP1A2
SCHEMBL30420033 0.80 LMNA (0.50) LMNACYP1A2HIF1ACYP2C19PTGS1
SCHEMBL10467747 0.80 MEN1 (0.40) MEN1KMT2AGAALMNACYP1A2
SCHEMBL8874204 0.78 MAOB (0.53) MAOBNR4A1NR4A2NR4A3MAPT
SCHEMBL9261991 0.78 RXRA (0.54) MEN1KMT2AGAAALDH1A1KDM4E
SCHEMBL23516408 0.78 GAA (0.47) MEN1KMT2AGAALMNACYP1A2
SCHEMBL9067574 0.77 ALDH1A1 (0.50) MEN1KMT2AGAALMNACYP1A2
SCHEMBL14518225 0.77 LMNA (0.53) MEN1KMT2AGAALMNACYP1A2
Phenol SCHEMBL20657088 0.77 MEN1 (0.55) MEN1KMT2AGAALMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208264-B2 Photothermographic material and method of forming images FUJIFILM CORPORATION (JP) 2007-04-24 US disclosed
US-7208264-B2 Photothermographic material and method of forming images FUJIFILM CORPORATION (JP) 2007-04-24 US disclosed
US-5418230-A Antiinflammatory SHIONOGI & CO., LTD. (JP) 1995-05-23 US disclosed