Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464779 | 0.86 | NPC1 (0.73) | RAB9ANPC1RXRARXRBMAPT | |
| SCHEMBL18259961 | 0.86 | NPC1 (0.73) | RAB9ANPC1RXRARXRBMAPT | |
| SCHEMBL11601531 | 0.85 | MAOB (0.69) | RAB9ANPC1RXRARXRBMAPT | |
| SCHEMBL4058623 | 0.85 | MAOB (0.69) | RAB9ANPC1RXRARXRBMAPT | |
| SCHEMBL528212 | 0.85 | CA1 (0.63) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1303551 | 0.84 | NPC1 (0.68) | RAB9ANPC1RXRARXRBMAPT | |
| SCHEMBL8016724 | 0.84 | PARP10 (0.58) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL18946710 | 0.83 | RAB9A (0.68) | RAB9ANPC1RXRARXRBMAPT | |
| SCHEMBL11603134 | 0.83 | MAOB (0.68) | RAB9ANPC1RXRARXRBMAPT | |
| SCHEMBL11601734 | 0.83 | MAOB (0.68) | RAB9ANPC1RXRARXRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399575-A | Antiallergens | BOEHRINGER MANNHEIM GMBH (DE) | 1995-03-21 | — | — | US | disclosed |