Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.62 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22540127 | 0.84 | PKM (0.46) | PKMKDM4EALDH1A1LMNAATM | |
| SCHEMBL16607680 | 0.80 | PKM (0.42) | PKMMMP8KDM4EMGAMGAA | |
| SCHEMBL10355716 | 0.78 | PKM (0.41) | PKMALDH1A1 | |
| SCHEMBL4763665 | 0.76 | PKM (0.44) | PKMMMP8KDM4EMGAMGAA | |
| SCHEMBL18430092 | 0.74 | PKM (0.43) | PKMMMP8KDM4EMGAMGAA | |
| SCHEMBL31252077 | 0.74 | PKM (0.46) | PKMMMP8KDM4EMGAMGAA | |
| SCHEMBL31251984 | 0.74 | PKM (0.43) | PKMMMP8KDM4EMGAMGAA | |
| SCHEMBL12654680 | 0.74 | PKM (0.43) | PKMMMP8KDM4EMGAMGAA | |
| SCHEMBL10154087 | 0.74 | PKM (0.43) | PKMMMP8KDM4EMGAMGAA | |
| SCHEMBL27739603 | 0.72 | PKM (0.50) | PKMMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7008985-B1 | Aerosol cement and valve for dispensing | GREEN RONALD D | 2006-03-07 | — | — | US | claimed |
| US-8445688-B2 | Process for producing enantiomer of amlodipine in high optical purity | EMCURE PHARMACEUTICALS LIMITED (IN) | 2013-05-21 | — | — | US | disclosed |
| US-20110021783-A1 | PROCESS FOR PRODUCING ENANTIOMER OF AMLODIPINE IN HIGH OPTICAL PURITY | EMCURE PHARMACEUTICALS LIMITED | 2011-01-27 | — | — | US | disclosed |
| US-7858801-B2 | Process for producing enantiomer of amlodipine in high optical purity | EMCURE PHARMACEUTICALS LIMITED (IN) | 2010-12-28 | — | — | US | disclosed |
| US-20080262239-A1 | Process for Producing Enantiomer of Amlodipine in High Optical Purity | EMCURE PHARMACEUTICALS LIMITED | 2008-10-23 | — | — | US | disclosed |
| EP-1802576-B1 | PROCESS FOR PRODUCING ENANTIOMER OF AMLODIPINE IN HIGH OPTICAL PURITY | EMCURE PHARMACEUTICALS LTD (IN) | 2008-06-25 | — | — | EP | disclosed |
| EP-1802576-A1 | PROCESS FOR PRODUCING ENANTIOMER OF AMLODIPINE IN HIGH OPTICAL PURITY | Emcure Pharmaceuticals Limited (IN) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006043148-A1 | PROCESS FOR PRODUCING ENANTIOMER OF AMLODIPINE IN HIGH OPTICAL PURITY | EMCURE PHARMACEUTICALS LIMITED (IN) | 2006-04-27 | — | — | WO | disclosed |
| CN-1473160-A | Indole derivatives as medicinal compositions for antifungal and/or antiparasitic agents | 杨池化学有限公司 | 2004-02-04 | — | — | CN | disclosed |
| CN-1020457-C | Process for preparing novel derivatives of 1-methyl-4, 5-dihydroorotic acid and pharmaceutical compositions thereof | TANABE SEIYAKU CO (JP) | 1993-05-05 | — | — | CN | disclosed |
| CN-86107574-A | Compositions containing penem or carbapenem antibiotics and their use | — | 1987-05-20 | — | — | CN | disclosed |
| CN-85105655-A | Process for preparing novel derivatives of 1-methyl-4, 5-dihydroorotic acid and pharmaceutical compositions thereof | — | 1987-01-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021783-A1 | PROCESS FOR PRODUCING ENANTIOMER OF AMLODIPINE IN HIGH OPTICAL PURITY | QDPR, DHODH, DHFR | PKM 3939/4885MMP8 4635/4885KDM4E 1628/4885 |
| US-20080262239-A1 | Process for Producing Enantiomer of Amlodipine in High Optical Purity | QDPR, DHODH, DHFR | PKM 3939/4885MMP8 4635/4885KDM4E 1628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.