Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129342 | 0.81 | QDPR (0.43) | QDPRALDH1A1KMT2A | |
| SCHEMBL9129304 | 0.78 | QDPR (0.41) | QDPR | |
| SCHEMBL14593825 | 0.75 | QDPR (0.39) | QDPRALDH1A1KMT2A | |
| SCHEMBL9129177 | 0.74 | QDPR (0.38) | QDPRALDH1A1KMT2A | |
| SCHEMBL7607024 | 0.72 | — | — | |
| SCHEMBL13001514 | 0.71 | HRH3 (0.46) | — | |
| SCHEMBL9127898 | 0.71 | ADRA2A (0.38) | QDPRALDH1A1KMT2A | |
| SCHEMBL6953079 | 0.71 | — | — | |
| SCHEMBL15370330 | 0.71 | — | — | |
| SCHEMBL4700734 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422353-A | Alzheimer*s disease, glaucoma treatment | BOEHRINGER INGELHEIM KG (DE) | 1995-06-06 | — | — | US | disclosed |
| EP-0325263-B1 | TETRAHYDROPYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM KG (DE) | 1992-09-23 | — | — | EP | disclosed |
| EP-0325263-A1 | Tetrahydropyridine derivatives | BOEHRINGER INGELHEIM KG (DE) | 1989-07-26 | — | — | EP | disclosed |