Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 1/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526073 | 0.88 | KMT2A (0.82) | ALDH1A1KMT2AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL12297966 | 0.85 | ALDH1A1 (0.61) | ALDH1A1KMT2AMAPTL3MBTL1GPR139 | |
| SCHEMBL8425114 | 0.84 | KMT2A (0.56) | ALDH1A1KMT2AMAPTL3MBTL1GPR139 | |
| SCHEMBL8748203 | 0.81 | KMT2A (0.53) | ALDH1A1KMT2AMAPTL3MBTL1GPR139 | |
| SCHEMBL14242027 | 0.80 | MAPT (0.70) | ALDH1A1KMT2AMAPTL3MBTL1TSHR | |
| SCHEMBL12642206 | 0.80 | GPR139 (0.62) | ALDH1A1KMT2AMAPTL3MBTL1GPR139 | |
| SCHEMBL8748201 | 0.80 | L3MBTL1 (0.55) | ALDH1A1KMT2AMAPTL3MBTL1GPR139 | |
| SCHEMBL9126255 | 0.79 | L3MBTL1 (0.72) | ALDH1A1MAPTL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL13333916 | 0.79 | MAPT (0.57) | ALDH1A1KMT2AMAPTL3MBTL1TSHR | |
| SCHEMBL8980470 | 0.78 | GPR139 (0.52) | ALDH1A1KMT2AMAPTL3MBTL1GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5421897-A | Applying liquid composition to surface contaminated with lead, solidifying into matrix which sequesters lead, removing matrix | GRAWE JOHN (US) | 1995-06-06 | — | — | US | claimed |
| US-5421897-A | Applying liquid composition to surface contaminated with lead, solidifying into matrix which sequesters lead, removing matrix | GRAWE JOHN (US) | 1995-06-06 | — | — | US | disclosed |
| US-5015448-A | Particulate material suitable for selectively separating metal cations from aqueous solutions, process for its production, and use thereof | GUTEC GESELLSCHAFT ZUR ENTWICKLUNG VON UMWELTSCHUTZTECHNOLOGIE MBH (DE) | 1991-05-14 | — | — | US | disclosed |