Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | LSS | P48449 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129697 | 0.88 | TBXAS1 (0.56) | TBXAS1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10837653 | 0.85 | ALDH1A1 (0.77) | TBXAS1KMT2AALDH1A1POLBLMNA | |
| SCHEMBL10838285 | 0.84 | ALDH1A1 (0.71) | TBXAS1ALDH1A1POLBCYP19A1 | |
| SCHEMBL9128618 | 0.84 | MEN1 (0.64) | KMT2AMEN1ALDH1A1TBXA2RPRMT1 | |
| SCHEMBL10836309 | 0.83 | ALDH1A1 (0.70) | TBXAS1ALDH1A1POLBCYP19A1 | |
| Hydrochloric Acid SCHEMBL10836734 | 0.82 | ALDH1A1 (0.68) | TBXAS1ALDH1A1POLBCYP19A1 | |
| SCHEMBL9754552 | 0.80 | MEN1 (0.84) | KMT2AMEN1ALDH1A1TBXA2RPRMT1 | |
| SCHEMBL9661115 | 0.80 | TBXA2R (0.62) | TBXAS1KMT2AMEN1ALDH1A1TBXA2R | |
| SCHEMBL9131822 | 0.79 | MEN1 (0.57) | TBXAS1KMT2AMEN1ALDH1A1TBXA2R | |
| SCHEMBL8309573 | 0.78 | TBXAS1 (1.00) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0564499-B1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |