Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129290 | 0.88 | TBXAS1 (0.63) | TBXAS1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8584574 | 0.86 | TBXAS1 (0.59) | TBXAS1KMT2AMEN1 | |
| SCHEMBL9128410 | 0.82 | SGMS1 (0.52) | TBXAS1KMT2ASGMS1MEN1F2 | |
| SCHEMBL10837653 | 0.79 | ALDH1A1 (0.77) | TBXAS1KMT2AALDH1A1 | |
| SCHEMBL9129703 | 0.78 | F2 (0.78) | TBXAS1KMT2ASGMS1MEN1F2 | |
| SCHEMBL9131391 | 0.78 | LSS (0.65) | KMT2ASGMS1MEN1LTA4HALDH1A1 | |
| SCHEMBL9128700 | 0.78 | MEN1 (0.65) | TBXAS1KMT2ASGMS1MEN1F2 | |
| SCHEMBL10838285 | 0.78 | ALDH1A1 (0.71) | TBXAS1ALDH1A1 | |
| SCHEMBL9128289 | 0.77 | LSS (0.55) | KMT2ASGMS1MEN1LTA4HALDH1A1 | |
| SCHEMBL10836309 | 0.77 | ALDH1A1 (0.70) | TBXAS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0564499-B1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |