Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.62 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.62 |
| ▸ | SGMS1 | Q86VZ5 | 4/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813017 | 0.91 | TBXA2R (0.75) | TBXA2RTBXAS1SGMS1AKR1C3ALDH1A1 | |
| SCHEMBL10773841 | 0.90 | ALDH1A1 (0.66) | TBXA2RTBXAS1SGMS1AKR1C3ALDH1A1 | |
| SCHEMBL9127503 | 0.89 | TBXA2R (0.69) | TBXA2RTBXAS1SGMS1AKR1C3CA12 | |
| SCHEMBL9128686 | 0.89 | TBXA2R (0.62) | TBXA2RTBXAS1SGMS1AKR1C3CA12 | |
| SCHEMBL9812942 | 0.89 | TBXA2R (0.62) | TBXA2RTBXAS1SGMS1AKR1C3CA12 | |
| SCHEMBL9129394 | 0.87 | SGMS1 (0.74) | SGMS1L3MBTL1ALDH1A1KMT2AMAPT | |
| SCHEMBL11371899 | 0.86 | TBXA2R (0.79) | TBXA2RTBXAS1SGMS1AKR1C3ALDH1A1 | |
| SCHEMBL9659360 | 0.86 | TBXA2R (0.58) | TBXA2RTBXAS1SGMS1AKR1C3CA12 | |
| SCHEMBL9836463 | 0.86 | TBXA2R (0.65) | TBXA2RTBXAS1SGMS1AKR1C3CA12 | |
| SCHEMBL9835966 | 0.86 | TBXA2R (0.61) | TBXA2RTBXAS1SGMS1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037990-A | Antagonist, antagonism, bronchodilator; antiischemic agents, treatment of cardiovascular disorder, kidney dialysis; and antiulcer agent | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | claimed |
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0564499-B1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0564499-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-13 | — | — | EP | disclosed |
| US-5173500-A | Inhibiting thrombocyte aggregation | BOEHRINGER MANNHEIM GMBH (DE) | 1992-12-22 | — | — | US | disclosed |
| WO-1992011234-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-07-09 | — | — | WO | disclosed |
| US-5037990-A | Antagonist, antagonism, bronchodilator; antiischemic agents, treatment of cardiovascular disorder, kidney dialysis; and antiulcer agent | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |
| CN-1045780-A | The preparation of new sulfonamide derivatives | BOEHRINGER MANNHEIM GMBH (DE) | 1990-10-03 | — | — | CN | disclosed |
| EP-0239907-A1 | Phenoxyalkanecarboxylic-acid derivatives, process for their preparation and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1987-10-07 | — | — | EP | disclosed |