Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.75 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.75 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.63 |
| ▸ | SGMS1 | Q86VZ5 | 6/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812947 | 0.93 | TBXA2R (0.65) | TBXA2RTBXAS1AKR1C3SGMS1TDP1 | |
| SCHEMBL9813009 | 0.92 | TBXA2R (0.63) | TBXA2RTBXAS1AKR1C3SGMS1TDP1 | |
| SCHEMBL9617068 | 0.91 | SGMS1 (0.63) | TBXA2RTBXAS1AKR1C3SGMS1ALDH1A1 | |
| SCHEMBL9128686 | 0.91 | TBXA2R (0.62) | TBXA2RTBXAS1AKR1C3SGMS1ALDH1A1 | |
| SCHEMBL9812942 | 0.91 | TBXA2R (0.62) | TBXA2RTBXAS1AKR1C3SGMS1ALDH1A1 | |
| SCHEMBL9127503 | 0.91 | TBXA2R (0.69) | TBXA2RTBXAS1AKR1C3SGMS1PRMT1 | |
| SCHEMBL9129388 | 0.91 | TBXA2R (0.62) | TBXA2RTBXAS1AKR1C3SGMS1ALDH1A1 | |
| SCHEMBL10773786 | 0.90 | TBXA2R (0.61) | TBXA2RTBXAS1AKR1C3SGMS1ALDH1A1 | |
| SCHEMBL10773841 | 0.90 | ALDH1A1 (0.66) | TBXA2RTBXAS1AKR1C3SGMS1ALDH1A1 | |
| SCHEMBL9836463 | 0.88 | TBXA2R (0.65) | TBXA2RTBXAS1AKR1C3SGMS1PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239907-B1 | PHENOXYALKANECARBOXYLIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1991-09-18 | — | — | EP | disclosed |
| EP-0223593-B1 | PHENOXYALKYLCARBOXYLIC ACIDS AND ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION | GLAXO GROUP LIMITED (GB) | 1991-08-07 | — | — | EP | disclosed |
| EP-0239907-A1 | Phenoxyalkanecarboxylic-acid derivatives, process for their preparation and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1987-10-07 | — | — | EP | disclosed |
| EP-0223593-A2 | Phenoxyalkylcarboxylic acids and esters and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1987-05-27 | — | — | EP | disclosed |