Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS1 | Q86VZ5 | 9/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129388 | 0.87 | TBXA2R (0.62) | SGMS1L3MBTL1ALDH1A1KMT2AMAPT | |
| SCHEMBL9617068 | 0.83 | SGMS1 (0.63) | SGMS1ALDH1A1LMNA | |
| SCHEMBL9130159 | 0.82 | DRD4 (0.55) | SGMS1L3MBTL1ALDH1A1KMT2ARAB9A | |
| SCHEMBL9128157 | 0.81 | LMNA (0.57) | SGMS1L3MBTL1ALDH1A1USP2HPGD | |
| SCHEMBL9130577 | 0.81 | SGMS1 (0.64) | SGMS1HTT | |
| SCHEMBL9813017 | 0.81 | TBXA2R (0.75) | SGMS1ALDH1A1MAPTHTT | |
| SCHEMBL9850482 | 0.80 | SGMS1 (0.66) | SGMS1 | |
| SCHEMBL30949337 | 0.80 | SGMS1 (1.00) | SGMS1ALDH1A1HTT | |
| SCHEMBL10773841 | 0.78 | ALDH1A1 (0.66) | SGMS1ALDH1A1KMT2AHTTLMNA | |
| SCHEMBL14142894 | 0.78 | ALDH1A1 (0.87) | L3MBTL1ALDH1A1USP2KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |