Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13997447 | 0.85 | GGPS1 (0.42) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL25615767 | 0.85 | GGPS1 (0.42) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL9129453 | 0.85 | ALDH1A1 (0.40) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL4139621 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL20515076 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL10727436 | 0.80 | CA12 (0.50) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL10727061 | 0.80 | CA12 (0.50) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL8015904 | 0.80 | CA12 (0.50) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL6708723 | 0.80 | CA12 (0.50) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL8398806 | 0.79 | MMP1 (0.46) | ALDH1A1HPGDMMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387596-A | Treating arteriosclerosis | SANKYO COMPANY, LIMITED (JP) | 1995-02-07 | — | — | US | disclosed |