Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398806 | 0.94 | MMP1 (0.46) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL25615767 | 0.85 | GGPS1 (0.42) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL13997447 | 0.85 | GGPS1 (0.42) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL9129441 | 0.85 | ALDH1A1 (0.40) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL20149583 | 0.80 | FFAR4 (0.62) | FFAR4FFAR1GPR84 | |
| SCHEMBL31271708 | 0.80 | FFAR4 (0.62) | FFAR4FFAR1GPR84 | |
| SCHEMBL31271753 | 0.80 | FFAR4 (0.62) | FFAR4FFAR1GPR84 | |
| SCHEMBL31272125 | 0.80 | FFAR4 (0.62) | FFAR4FFAR1GPR84 | |
| SCHEMBL10727061 | 0.80 | CA12 (0.50) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL4139621 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HPGDMMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387596-A | Treating arteriosclerosis | SANKYO COMPANY, LIMITED (JP) | 1995-02-07 | — | — | US | disclosed |