Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713765 | 0.94 | DGKA (0.61) | DGKAALDH1A1PAMTSHRMAPT | |
| SCHEMBL8451218 | 0.92 | DGKA (0.64) | DGKAALDH1A1PAMTSHRMAPT | |
| SCHEMBL7715347 | 0.92 | DGKA (0.64) | DGKAALDH1A1PAMTSHRMAPT | |
| SCHEMBL7716049 | 0.92 | DGKA (0.64) | DGKAALDH1A1PAMTSHRMAPT | |
| SCHEMBL7709809 | 0.92 | DGKA (0.64) | DGKAALDH1A1PAMTSHRMAPT | |
| SCHEMBL7881165 | 0.92 | DGKA (0.64) | DGKAALDH1A1PAMTSHRMAPT | |
| SCHEMBL10099629 | 0.89 | DGKA (0.62) | DGKAALDH1A1TP53PAMTSHR | |
| SCHEMBL5210881 | 0.86 | ALDH1A1 (0.50) | DGKAALDH1A1TP53PAMTSHR | |
| SCHEMBL7783180 | 0.84 | DGKA (0.46) | DGKAALDH1A1PAMTSHRMAPT | |
| SCHEMBL3834162 | 0.81 | DGKA (0.74) | DGKAALDH1A1PAMTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401868-A | Sulfiding and esterification to form chemical intermediates | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUCTIONSAKTIESELSKAB) (DK) | 1995-03-28 | — | — | US | claimed |
| EP-0541550-B1 | NEW INTERMEDIATES, THEIR PRODUCTION AND USE | LEO PHARM PROD LTD (DK) | 1994-09-07 | — | — | EP | claimed |