SCHEMBL9129709

SCHEMBL9129709

CC(Cc1ccc2cc(C(=O)O)ccc2c1)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.50
GRIN2A Q12879 1/20 0.50
GRIN2B Q13224 1/20 0.50
GRIN2C Q14957 1/20 0.50
KDM4E B2RXH2 1/20 0.42
TBXAS1 P24557 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
RARB P10826 2/20 0.39
RARG P13631 2/20 0.39
RARA P10276 1/20 0.39
PTPN1 P18031 1/20 0.37
RXRA P19793 2/20 0.36
RXRB P28702 2/20 0.36
NR4A2 P43354 2/20 0.36
HCAR3 P49019 1/20 0.36
NR4A1 P22736 1/20 0.36
NR4A3 Q92570 1/20 0.36
CASR P41180 1/20 0.36
NR1H4 Q96RI1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9127812 0.91 GRIN2D (0.40) GRIN2DGRIN2AGRIN2BGRIN2CKMT2A
SCHEMBL8716903 0.83 ADRB1 (0.45) MEN1KMT2ARARBRARARXRA
SCHEMBL10747697 0.79 GRIN2D (0.58) GRIN2DGRIN2AGRIN2BGRIN2CKDM4E
SCHEMBL9129713 0.76 IKBKE (0.32)
SCHEMBL8719655 0.76 MMP12 (0.43) MEN1KMT2ANR1H4
SCHEMBL9126436 0.76 GRIN2D (0.61) GRIN2DGRIN2AGRIN2BGRIN2CKDM4E
SCHEMBL9128075 0.75 GRIN2D (0.53) GRIN2DGRIN2AGRIN2BGRIN2CKDM4E
SCHEMBL18109853 0.73 TDP1 (0.38) GRIN2DGRIN2AGRIN2BGRIN2CKDM4E
SCHEMBL9320800 0.73 GRIN2D (0.52) GRIN2DGRIN2AGRIN2BGRIN2CMEN1
SCHEMBL9127842 0.73 GRIN2D (0.51) GRIN2DGRIN2AGRIN2BGRIN2CKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5422038-A Ferroelectric liquid crystal material with sufficient spontaneous polarization, high speed response capability, wide temperature range SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-06-06 US disclosed
EP-0416946-B1 Optically active naphthalene derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same SUMITOMO CHEMICAL CO (JP) 1994-11-09 EP disclosed
EP-0416946-A2 Optically active naphthalene derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-03-13 EP disclosed