Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716903 | 0.90 | ADRB1 (0.45) | MAPTKMT2AMEN1ALDH1A1ADRB1 | |
| SCHEMBL9127812 | 0.83 | GRIN2D (0.40) | MAPTSMN1; SMN2KMT2APPARGPPARA | |
| SCHEMBL12002631 | 0.80 | SIGMAR1 (0.38) | SMN1; SMN2KMT2APPARGPPARAMEN1 | |
| SCHEMBL12002733 | 0.80 | SIGMAR1 (0.38) | SMN1; SMN2KMT2APPARGPPARAMEN1 | |
| SCHEMBL8155949 | 0.77 | SMN1; SMN2 (0.50) | MMP12MMP13MAPTSMN1; SMN2KMT2A | |
| SCHEMBL254987 | 0.77 | MAPT (0.55) | MAPTLMNAALDH1A1HPGDMAOB | |
| SCHEMBL9129709 | 0.76 | GRIN2D (0.50) | KMT2AMEN1NR1H4 | |
| SCHEMBL13594158 | 0.76 | SIGMAR1 (0.44) | KMT2AMEN1 | |
| SCHEMBL3857268 | 0.75 | APLNR (0.39) | KMT2APPARGPPARAACACBMEN1 | |
| SCHEMBL3863324 | 0.74 | LPL (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741438-A | Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as an effective component, and liquid crystal element using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-21 | — | — | US | disclosed |
| EP-0395390-B1 | Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same | SUMITOMO CHEMICAL CO (JP) | 1994-09-28 | — | — | EP | disclosed |