Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CTSD | P07339 | 4/20 | 0.36 |
| ▸ | BACE1 | P56817 | 4/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130201 | 0.83 | MAPT (0.39) | L3MBTL1LMNAALDH1A1CRHBPCRHR2 | |
| SCHEMBL9019554 | 0.83 | MAPT (0.39) | L3MBTL1LMNAALDH1A1CRHBPCRHR2 | |
| SCHEMBL9127050 | 0.83 | ALDH1A1 (0.37) | L3MBTL1LMNAALDH1A1CRHBPCRHR2 | |
| SCHEMBL9019616 | 0.83 | ALDH1A1 (0.37) | L3MBTL1LMNAALDH1A1CRHBPCRHR2 | |
| SCHEMBL9127537 | 0.82 | LMNA (0.39) | L3MBTL1LMNATSHRALDH1A1 | |
| SCHEMBL9019607 | 0.80 | LMNA (0.33) | L3MBTL1LMNA | |
| SCHEMBL9131101 | 0.80 | LMNA (0.33) | L3MBTL1LMNA | |
| SCHEMBL9019595 | 0.77 | LMNA (0.36) | LMNA | |
| SCHEMBL9128912 | 0.77 | LMNA (0.36) | LMNA | |
| SCHEMBL9127158 | 0.74 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411989-A | Cardiovascular disorders | BOEHRINGER MANNHEIM, GMBH (DE) | 1995-05-02 | — | — | US | disclosed |