Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CRHBP | P24387 | 2/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130201 | 1.00 | MAPT (0.39) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL9019616 | 0.84 | ALDH1A1 (0.37) | MAPTKDM4EALDH1A1CRHBPCRHR2 | |
| SCHEMBL9127050 | 0.84 | ALDH1A1 (0.37) | MAPTKDM4EALDH1A1CRHBPCRHR2 | |
| SCHEMBL9130221 | 0.83 | L3MBTL1 (0.44) | ALDH1A1CRHBPCRHR2L3MBTL1LMNA | |
| SCHEMBL6439317 | 0.78 | BCHE (0.38) | KDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL6439306 | 0.78 | BCHE (0.38) | KDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL9127502 | 0.78 | BCHE (0.33) | KMT2A | |
| SCHEMBL9127652 | 0.77 | BCHE (0.35) | LMNAKMT2A | |
| SCHEMBL9131101 | 0.76 | LMNA (0.33) | L3MBTL1LMNAKMT2A | |
| SCHEMBL9019607 | 0.76 | LMNA (0.33) | L3MBTL1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515420-B1 | NITRIC ACID ESTERS OF CYCLOHEXANOL DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 1996-06-12 | — | — | EP | disclosed |