Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9131926 | 0.94 | MTNR1A (0.56) | MTNR1AMTNR1BMEN1POLBKMT2A | |
| SCHEMBL31176222 | 0.94 | MTNR1A (0.56) | MTNR1AMTNR1BMEN1POLBKMT2A | |
| SCHEMBL8097845 | 0.94 | MTNR1A (0.56) | MTNR1AMTNR1BMEN1POLBKMT2A | |
| SCHEMBL14615541 | 0.92 | SLC6A4 (0.51) | MTNR1AMTNR1BCES2 | |
| SCHEMBL9491275 | 0.84 | MTNR1A (0.65) | MTNR1AMTNR1B | |
| SCHEMBL22160722 | 0.83 | MC4R (0.63) | CES2POLBCYP2C19 | |
| SCHEMBL22178785 | 0.83 | MC4R (0.63) | CES2POLBCYP2C19 | |
| SCHEMBL22178784 | 0.83 | MC4R (0.63) | CES2POLBCYP2C19 | |
| SCHEMBL23417495 | 0.81 | CYP2C19 (0.68) | MEN1POLBKMT2ACYP2C19TSHR | |
| SCHEMBL7439966 | 0.80 | CES2 (0.52) | MTNR1AMTNR1BCES2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420158-A | Melatonin activity | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |