Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9131926 | 0.97 | MTNR1A (0.56) | MTNR1AMTNR1BSMN1; SMN2NPC1PKM | |
| SCHEMBL31176222 | 0.97 | MTNR1A (0.56) | MTNR1AMTNR1BSMN1; SMN2NPC1PKM | |
| SCHEMBL9130436 | 0.94 | MTNR1A (0.54) | MTNR1AMTNR1BTSHRMEN1KMT2A | |
| SCHEMBL14615541 | 0.89 | SLC6A4 (0.51) | MTNR1AMTNR1BSMN1; SMN2ALDH1A1 | |
| SCHEMBL8083501 | 0.86 | ERCC1 (0.65) | ALDH1A1ALOX12MEN1KMT2AALOX15 | |
| SCHEMBL9490611 | 0.85 | MTNR1A (0.64) | MTNR1AMTNR1BALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL9490284 | 0.84 | MTNR1A (0.65) | MTNR1AMTNR1BALDH1A1HSD17B10MEN1 | |
| SCHEMBL7439966 | 0.83 | CES2 (0.52) | MTNR1AMTNR1BSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL9491966 | 0.82 | MTNR1A (0.64) | MTNR1AMTNR1BALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL13138659 | 0.81 | ALDH1A1 (0.74) | SMN1; SMN2NPC1PKMEPHX2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |