Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10461554 | 0.79 | TBXA2R (0.76) | TBXA2RALDH1A1MAPTAKR1C3TBXAS1 | |
| SCHEMBL11108606 | 0.78 | L3MBTL1 (0.59) | TBXA2RALDH1A1MAPTL3MBTL1AKR1B1 | |
| SCHEMBL11109419 | 0.76 | TBXA2R (0.60) | TBXA2RALDH1A1MAPTAKR1B1TBXAS1 | |
| SCHEMBL11357235 | 0.75 | ESRRG (0.68) | ALDH1A1L3MBTL1HDAC2HDAC8HDAC6 | |
| SCHEMBL4163523 | 0.74 | MMP12 (0.50) | MAPTL3MBTL1GAATSHRMAPK1 | |
| SCHEMBL11105698 | 0.73 | TBXA2R (0.56) | TBXA2RALDH1A1MAPTL3MBTL1AKR1C3 | |
| SCHEMBL11107861 | 0.73 | GAA (0.63) | TBXA2RALDH1A1MAPTAKR1B1TBXAS1 | |
| SCHEMBL11107857 | 0.73 | GAA (0.63) | TBXA2RALDH1A1MAPTAKR1B1TBXAS1 | |
| SCHEMBL9718382 | 0.73 | KMT2A (0.57) | TBXA2RALDH1A1MAPTL3MBTL1AKR1C3 | |
| SCHEMBL11108980 | 0.72 | TBXA2R (0.75) | TBXA2RALDH1A1MAPTAKR1C3TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |