SCHEMBL9130454

SCHEMBL9130454

COc1ccc(C(=CC(=O)O)Oc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.54
CES1 P23141 2/20 0.54
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
ALDH1A1 P00352 4/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
MAPT P10636 1/20 0.49
HSPD1 P10809 1/20 0.49
TNFRSF1A P19438 1/20 0.49
MAOB P27338 1/20 0.49
HSPE1 P61604 1/20 0.49
CYP1B1 Q16678 1/20 0.49
GAA P10253 3/20 0.47
HTT P42858 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 2/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
HPGD P15428 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28947530 0.83 CA1 (0.60) CES2CES1CA1CA2ALDH1A1
SCHEMBL4390225 0.78 CES2 (0.65) CES2CES1CA1CA2ALDH1A1
SCHEMBL4394754 0.78 CES2 (0.65) CES2CES1CA1CA2ALDH1A1
SCHEMBL4394758 0.78 CES2 (0.65) CES2CES1CA1CA2ALDH1A1
SCHEMBL27765368 0.78 KMT2A (0.66) CES2CES1CA1CA2ALDH1A1
SCHEMBL18088853 0.78 KMT2A (0.66) CES2CES1CA1CA2ALDH1A1
SCHEMBL7633148 0.78 KMT2A (0.66) CES2CES1CA1CA2ALDH1A1
SCHEMBL6662868 0.78 CES2 (0.53) CES2CES1CA1CA2ALDH1A1
SCHEMBL17714706 0.75 CA1 (0.61) CES2CES1CA1CA2ALDH1A1
SCHEMBL2019776 0.75 CA1 (0.61) CES2CES1CA1CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7053451-A None JP disclosed
JP-H0753451-A ALPHA-OXYCINNAMIC ACID DERIVATIVE, ULTRAVIOLET LIGHT ABSORBER AND COSMETIC CONTAINING THE SAME KAO CORP 1995-02-28 JP disclosed