SCHEMBL7633148

SCHEMBL7633148

COc1ccc(C(=O)Oc2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.66
SMN1; SMN2 Q16637 3/20 0.66
LMNA P02545 1/20 0.66
CYP1A2 P05177 1/20 0.66
CYP2C9 P11712 1/20 0.66
CYP2C19 P33261 1/20 0.66
CES2 O00748 2/20 0.63
CES1 P23141 2/20 0.63
PARP10 Q53GL7 1/20 0.62
CA1 P00915 2/20 0.62
CA2 P00918 2/20 0.62
MAPT P10636 5/20 0.61
PRSS1 P07477 2/20 0.61
ACR P10323 2/20 0.61
GFER P55789 1/20 0.61
MEN1 O00255 2/20 0.59
PKM P14618 2/20 0.59
ALDH1A1 P00352 2/20 0.59
TDP1 Q9NUW8 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18088853 1.00 KMT2A (0.66) KMT2ASMN1; SMN2LMNACYP1A2CYP2C9
SCHEMBL27765368 1.00 KMT2A (0.66) KMT2ASMN1; SMN2LMNACYP1A2CYP2C9
SCHEMBL16429579 0.96 CES2 (0.69) KMT2ASMN1; SMN2LMNACYP1A2CYP2C9
SCHEMBL18088852 0.95 KMT2A (0.60) KMT2ASMN1; SMN2LMNACYP1A2CYP2C9
SCHEMBL1546266 0.94 SMN1; SMN2 (0.68) KMT2ASMN1; SMN2LMNACYP1A2CYP2C9
SCHEMBL7591660 0.92 LMNA (0.75) KMT2ASMN1; SMN2LMNACYP1A2CYP2C9
SCHEMBL9666088 0.92 LMNA (0.75) KMT2ASMN1; SMN2LMNACYP1A2CYP2C9
SCHEMBL12633724 0.92 LMNA (0.75) KMT2ASMN1; SMN2LMNACYP1A2CYP2C9
SCHEMBL12608584 0.92 LMNA (0.75) KMT2ASMN1; SMN2LMNACYP1A2CYP2C9
Iodobenzene SCHEMBL27765170 0.92 KMT2A (0.57) KMT2ASMN1; SMN2LMNACYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9656927-B2 Process for the synthesis of carboxylic acid derivatives COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2017-05-23 US claimed
US-20160272554-A1 PROCESS FOR THE SYNTHESIS OF CARBOXYLIC ACID DERIVATIVES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-09-22 US claimed
WO-2015063798-A1 A PROCESS FOR THE SYNTHESIS OF CARBOXYLIC ACID DERIVATIVES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-05-07 WO claimed
JP-63048331-A None JP disclosed
CN-119708924-A Ink, ink preparation method and ink-jet printing method 广东聚华印刷显示技术有限公司 2025-03-28 CN disclosed
CN-115724772-A Compound with urea structure and preparation and application thereof 云南大学 2023-03-03 CN disclosed
CN-112110817-B Method for preparing diaryl ester compound by high-efficiency catalysis of palladium pyridine 陕西师范大学 2022-07-26 CN disclosed
CN-112110817-A Method for preparing diaryl ester compound by high-efficiency catalysis of palladium pyridine 陕西师范大学 2020-12-22 CN disclosed
CN-106699717-B A ring trimethoxy flavone substituted salicylic acid esters compound and its antitumor action 南华大学 2019-04-09 CN disclosed
CN-108517022-A For the ingredient of solid catalyst and its catalyst of olefinic polymerization and application 北京利和知信科技有限公司 2018-09-11 CN disclosed
CN-108517021-A A kind of ingredient of solid catalyst, catalyst and its application being suitable for producing broad molecular weight distribution polymers 北京利和知信科技有限公司 2018-09-11 CN disclosed
US-4400543-A ANTIFERTILITY AGENTS ELI LILLY AND COMPANY (US) 1983-08-23 US disclosed
US-4361563-A CARDIOTONIC, ANTITHROMBOTIC DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-11-30 US disclosed
EP-0057503-A1 Production of hydroxy arylophenones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-08-11 EP disclosed
EP-0050497-A1 Catalyst components for polymerization of alpha-olefins and processes for their preparation and use TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1982-04-28 EP disclosed
US-4323707-A USEFUL FOR AMIMALS, AROYL-PHENYL-NAPHTHALENES OR DIHYDRONAPHTHALENES ELI LILLY AND COMPANY (US) 1982-04-06 US disclosed
US-4230862-A 3-PHENYL-4-AROYL-1,2-DIHYDRONAPHTHALENES AND 1-ARYOYL-2-PHENYLNAPHTHALENES ELI LILLY AND COMPANY (US) 1980-10-28 US disclosed
US-4075223-A NONSTEROIDAL ELI LILLY AND COMPANY (US) 1978-02-21 US disclosed
US-4026891-A HYPOTENSIVE AGENTS, ANTITHROMBOTICS, AND CARDIOTONICS BOEHRINGER INGELHEIM GMBH (DT) 1977-05-31 US disclosed
US-4017546-A AROYL PHENYL INDENES AND AROYL PHENYL NAPHTHALENES ELI LILLY AND COMPANY (US) 1977-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160272554-A1 PROCESS FOR THE SYNTHESIS OF CARBOXYLIC ACID DERIVATIVES PCCA, CPS1, CS KMT2A 1512/4885SMN1; SMN2 2870/4885LMNA 3768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.