Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129942 | 0.94 | HTR1A (0.53) | HTR1AHTR2AHTR7DRD2HTR6 | |
| SCHEMBL9131296 | 0.94 | HTR1A (0.51) | HTR1AHTR2AHTR7DRD2HTR6 | |
| SCHEMBL9131001 | 0.94 | HTR1A (0.54) | HTR1AHTR2AHTR7DRD2HTR6 | |
| SCHEMBL9131963 | 0.91 | HTR1A (0.45) | HTR1AHTR2AHTR7DRD2SMN1; SMN2 | |
| SCHEMBL9130474 | 0.90 | HTR1A (0.57) | HTR1AHTR2AHTR7DRD2HTR6 | |
| SCHEMBL9130405 | 0.86 | HTR2A (0.38) | HTR2AHTR7SMN1; SMN2 | |
| SCHEMBL9131814 | 0.86 | HTR1A (0.47) | HTR1AHTR2AHTR7DRD2HTR6 | |
| SCHEMBL9129953 | 0.85 | HTR1A (0.52) | HTR1AHTR2AHTR7DRD2HTR6 | |
| SCHEMBL9129907 | 0.85 | HTR1A (0.50) | HTR1AHTR2AHTR7DRD2HTR6 | |
| SCHEMBL9131290 | 0.85 | HTR1A (0.62) | HTR1AHTR2AHTR7DRD2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453437-A | 1,3-disubstituted pyrrolidines | BAYER AKTIENGESELLSCHAFT (DE) | 1995-09-26 | — | — | US | disclosed |
| US-5274097-A | A 1-N-heterocyclic alkylene-3-carbo or heterocyclic ring oxypyrrolidine derivative | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |
| US-5037841-A | For treating nervous system disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-06 | — | — | US | disclosed |