Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130995 | 0.90 | L3MBTL1 (0.45) | LMNAPOLBMAPTNLRP3GAA | |
| SCHEMBL9131666 | 0.88 | PLK1 (0.46) | LMNAPOLBMAPTNLRP3MEN1 | |
| SCHEMBL9130515 | 0.82 | LMNA (0.58) | LMNAPOLBMAPTNLRP3GAA | |
| SCHEMBL9129497 | 0.82 | LMNA (0.57) | LMNAPOLBMAPTNLRP3GAA | |
| SCHEMBL9132201 | 0.80 | PLK1 (0.47) | LMNAPOLBMEN1KMT2ARAB9A | |
| SCHEMBL9131340 | 0.80 | LMNA (0.55) | LMNAPOLBMAPTNLRP3GAA | |
| SCHEMBL9130510 | 0.79 | LMNA (0.47) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL9128707 | 0.78 | MAPT (0.50) | LMNAPOLBMAPTGAANPSR1 | |
| SCHEMBL9130894 | 0.77 | LMNA (0.59) | LMNAPOLBMAPTNLRP3MEN1 | |
| SCHEMBL9713765 | 0.73 | LMNA (0.52) | LMNAPOLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399703-A | Antiallergens | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0536400-A1 | TETRAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-14 | — | — | EP | disclosed |