Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130515 | 0.89 | LMNA (0.58) | LMNAPOLBMAPTCACNA1HCACNA1B | |
| SCHEMBL9129746 | 0.80 | MAPT (0.52) | LMNAPOLBMAPTCACNA1HCACNA1B | |
| SCHEMBL9132468 | 0.79 | CACNA1H (0.52) | LMNAPOLBMAPTCACNA1HCACNA1B | |
| SCHEMBL1251594 | 0.78 | GAA (0.62) | POLBMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL9129497 | 0.78 | LMNA (0.57) | LMNAPOLBMAPTRAB9AMEN1 | |
| SCHEMBL9130553 | 0.77 | LMNA (0.56) | LMNAPOLBMAPTRAB9AMEN1 | |
| SCHEMBL9130795 | 0.77 | CACNA1H (0.50) | LMNAPOLBMAPTCACNA1HCACNA1B | |
| SCHEMBL8770347 | 0.77 | EPHX2 (0.51) | LMNAPOLBMAPTRAB9AMEN1 | |
| SCHEMBL9131340 | 0.77 | LMNA (0.55) | LMNAPOLBMAPTRAB9AMEN1 | |
| SCHEMBL1668701 | 0.76 | EPHX2 (0.59) | LMNAPOLBMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399703-A | Antiallergens | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0536400-A1 | TETRAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-14 | — | — | EP | disclosed |